Muzamil started his musical career as a guitarist when he was 14 years old. He has been learning guitars since he was 10 years old.He performed his first concert at US embassy in Islamabad then he has performed at national and international level. He has also been a recording artist at various studios recording guitars for a variety of artists .
In 2019 he appeared on Nescafe Basement season 5, and recently he has also been featured in Coke studio season 14, he played Sarod in that season; Muzamil is the only youngest Sarod player in Pakistan, an instrument that is on the edge of extinction.